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Clinical Medicine
Scientific Show Stopper
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238 Posts
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Mind the gap (junction)
Kazusaku Kamiya and colleagues developed murine models of CX26-dependant deafness to examine the underlying etiology of hearing loss in these animals...
Published March 3, 2014
Scientific Show Stopper
Lung allograft acceptance
Alexander Krupnick and colleagues have identified a surprising link between lung allograft survival and infiltration of central memory CD8+ T cells into the transplanted tissue...
Published February 25, 2014
Scientific Show Stopper
Linking a tumor suppressor to cardiac disease
Yoko Kojima and colleagues provide evidence that reduction of CDKN2B promotes atherosclerosis via reduced efferocytosis.....
Published February 17, 2014
Scientific Show Stopper
The FUS about familial amyotrophic lateral sclerosis
Haiyan Qiu, Sebum Lee and colleagues developed a transgenic mouse model of familial amyotrophic lateral sclerosis (FALS)...
Published February 10, 2014
Scientific Show Stopper
Tie1 on for angiogenesis
Current therapies aimed at limiting tumor angiogenesis are based on our understanding of factors that regulate blood vessel sprouting during growth and development. For example, inhibition of...
Published January 16, 2014
Scientific Show Stopper
Shedding light on age-promoting agents
Multiple tools have been established to readily evaluate the carcinogenic potential of environmental agents; however, few options are available to examine the ability of an environmental agent to...
Published December 16, 2013
Scientific Show Stopper
Sugar rush
Metabolic changes within the tumor microenvironment include increased glycolysis; however, it not clear if enhanced glycolytic activity is the result of tumorigenesis or an...
Published December 9, 2013
Scientific Show Stopper
Looking through the fog
PTEN hamartoma syndrome (PHTS) is a diverse syndrome that develops as the result of mutations in the gene encoding the tumor suppressor PTEN. Cataract formation is common in PHTS patients;...
Published November 25, 2013
Scientific Show Stopper
Filtration barriers
The kidney is responsible for retaining essential proteins and removing waste products from the blood stream. The kidney filter is maintained by an intricate structure formed by the actin-rich...
Published November 15, 2013
Scientific Show Stopper
Maintaining the neuromuscular junction
Patients suffering from myasthenia gravis (MG) have debilitating muscle weakness and fatigue. MG is the result of neuromuscular junction (NMJ) dysfunction ...
Published November 8, 2013
Scientific Show Stopper
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