Indomethacin potentiates the vasoconstrictor actions of angiotensin II in normal man
P Negus, RL Tannen, MJ Dunn - Prostaglandins, 1976 - Elsevier
The blood pressure response to graded infusions of angiotensin II was assessed under
control conditions and following short term (16 hour) indomethacin treatment utilizing normal
men equilibrated on a constant diet of normal sodium and potassium content. Although
basal mean blood pressure was unchanged, the increase in blood pressure with all rates of
angiotensin II infusion ranging from 200 to 1000 ng/min was significantly greater with
indomethacin treatment. Pre-infusion body weight and plasma renin activity were similar …
control conditions and following short term (16 hour) indomethacin treatment utilizing normal
men equilibrated on a constant diet of normal sodium and potassium content. Although
basal mean blood pressure was unchanged, the increase in blood pressure with all rates of
angiotensin II infusion ranging from 200 to 1000 ng/min was significantly greater with
indomethacin treatment. Pre-infusion body weight and plasma renin activity were similar …