Temporal alterations in basement membrane components in the pulmonary vasculature of the chronically hypoxic rat: impact of hypoxia and recovery
AC Vyas-Somani, SM Aziz, SA Arcot… - The American journal of …, 1996 - Elsevier
The hypoxic model of pulmonary hypertension was used to examine temporal alterations in
the deposition of the basement membrane (BM) and components of fibronectin, laminin, and
Type IV collagen within vascular, airway, and gas exchange compartments of the lung.
Because hypoxic pulmonary hypertension is a reversible model of hypertension, changes in
fibronectin and laminin synthesis/deposition in the recovering lung were also examined.
Long-term hypoxic exposure produced decreases in body weight, increased right ventricular …
the deposition of the basement membrane (BM) and components of fibronectin, laminin, and
Type IV collagen within vascular, airway, and gas exchange compartments of the lung.
Because hypoxic pulmonary hypertension is a reversible model of hypertension, changes in
fibronectin and laminin synthesis/deposition in the recovering lung were also examined.
Long-term hypoxic exposure produced decreases in body weight, increased right ventricular …