The emergence of definitive hematopoietic stem cells in the mammal
E Dzierzak - Current opinion in hematology, 2005 - journals.lww.com
E Dzierzak
Current opinion in hematology, 2005•journals.lww.comSeveral mammalian embryonic tissues contribute to the growth and/or generation of potent
HSCs that are the source of blood cells throughout the lifespan of the individual. Insight into
how mammalian HSC fate is determined has been provided through functional, phenotypic,
and genetic studies at early developmental stages.
HSCs that are the source of blood cells throughout the lifespan of the individual. Insight into
how mammalian HSC fate is determined has been provided through functional, phenotypic,
and genetic studies at early developmental stages.
Summary
Several mammalian embryonic tissues contribute to the growth and/or generation of potent HSCs that are the source of blood cells throughout the lifespan of the individual. Insight into how mammalian HSC fate is determined has been provided through functional, phenotypic, and genetic studies at early developmental stages.
Lippincott Williams & Wilkins