Although official magnesium (Mg) dietary reference intakes are open to question, a
significant number of adults likely have intakes that are in the range of 50%-99% of the
requirement. This moderate or marginal (subclinical) deficient Mg intake generally is
asymptomatic. Animal studies, however, indicate that moderate or subclinical Mg deficiency
primes phagocytic cells for the release of proinflammatory cytokines leading to chronic
inflammatory and oxidative stress. Human studies have found that dietary Mg is inversely …