Angiogenic factors at diagnosis of late-onset small-for-gestational age and histological placental underperfusion

S Triunfo, S Lobmaier, M Parra-Saavedra, F Crovetto… - Placenta, 2014 - Elsevier
Objective This study was designed to explore the association between angiogenic factors
levels at diagnosis of small-for-gestational age (SGA) and placental underperfusion (PUP).
Methods In a cohort of SGA singleton pregnancies, each delivered at> 34 weeks, uterine
(UtA), umbilical (UA), and middle cerebral (MCA) arteries were evaluated by Doppler upon
diagnosis of SGA status. In addition, maternal circulating concentrations of placental growth
factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1) were assayed by ELISA, and …