Diagnostic utility of serial circulating placental growth factor levels and uterine artery Doppler waveforms in diagnosing underlying placental diseases in pregnancies …

S Agrawal, WT Parks, HD Zeng, A Ravichandran… - American Journal of …, 2022 - Elsevier
Background Placental pathology assessment following delivery in pregnancies complicated
by preeclampsia, fetal growth restriction, abruption, and stillbirth reveals a range of
underlying diseases. The most common pathology is maternal vascular malperfusion,
characterized by high-resistance uterine artery Doppler waveforms and abnormal
expression of circulating maternal angiogenic growth factors. Rare placental diseases
(massive perivillous fibrinoid deposition and chronic histiocytic intervillositis) are reported to …