COVID-19 and multiorgan response

S Zaim, JH Chong, V Sankaranarayanan… - Current problems in …, 2020 - Elsevier
Since the outbreak and rapid spread of COVID-19 starting late December 2019, it has been
apparent that disease prognosis has largely been influenced by multiorgan involvement.
Comorbidities such as cardiovascular diseases have been the most common risk factors for
severity and mortality. The hyperinflammatory response of the body, coupled with the
plausible direct effects of severe acute respiratory syndrome on body-wide organs via
angiotensin-converting enzyme 2, has been associated with complications of the disease …