[HTML][HTML] Peptidoglycan recognition proteins involved in 1, 3-β-D-glucan-dependent prophenoloxidase activation system of insect
MH Lee, T Osaki, JY Lee, MJ Baek, R Zhang… - Journal of biological …, 2004 - ASBMB
The prophenoloxidase (proPO) cascade is a major innate immune response in
invertebrates, which is triggered into its active form by elicitors, such as lipopolysaccharide,
peptidoglycan, and 1, 3-β-d-glucan. A key question of the proPO system is how pattern
recognition proteins recognize pathogenic microbes and subsequently activate the system.
To investigate the biological function of 1, 3-β-d-glucan pattern recognition protein in the
proPO cascade system, we isolated eight different 1, 3-β-d-glucan-binding proteins from the …
invertebrates, which is triggered into its active form by elicitors, such as lipopolysaccharide,
peptidoglycan, and 1, 3-β-d-glucan. A key question of the proPO system is how pattern
recognition proteins recognize pathogenic microbes and subsequently activate the system.
To investigate the biological function of 1, 3-β-d-glucan pattern recognition protein in the
proPO cascade system, we isolated eight different 1, 3-β-d-glucan-binding proteins from the …
