[HTML][HTML] Is ghrelin a biomarker for mortality in end-stage renal disease?
RH Mak, WW Cheung - Kidney international, 2011 - Elsevier
RH Mak, WW Cheung
Kidney international, 2011•ElsevierGhrelin is involved in the pathogenesis of protein-energy wasting (PEW), inflammation, and
cardiovascular complications in end-stage renal disease (ESRD). Plasma ghrelin may prove
to be a powerful biomarker of mortality in ESRD but should be considered in the context of
assay specificity, other weight-regulating hormones, nutritional status, systemic
inflammation, and cardiovascular risk factors. ESRD patients with PEW, systemic
inflammation, and low ghrelin and high leptin concentrations have the highest mortality risk …
cardiovascular complications in end-stage renal disease (ESRD). Plasma ghrelin may prove
to be a powerful biomarker of mortality in ESRD but should be considered in the context of
assay specificity, other weight-regulating hormones, nutritional status, systemic
inflammation, and cardiovascular risk factors. ESRD patients with PEW, systemic
inflammation, and low ghrelin and high leptin concentrations have the highest mortality risk …
Ghrelin is involved in the pathogenesis of protein-energy wasting (PEW), inflammation, and cardiovascular complications in end-stage renal disease (ESRD). Plasma ghrelin may prove to be a powerful biomarker of mortality in ESRD but should be considered in the context of assay specificity, other weight-regulating hormones, nutritional status, systemic inflammation, and cardiovascular risk factors. ESRD patients with PEW, systemic inflammation, and low ghrelin and high leptin concentrations have the highest mortality risk and may benefit the most from ghrelin therapy.
Elsevier
