Beclin 1 expression predicts favorable clinical outcome in patients with diffuse large B-cell lymphoma treated with R-CHOP
JJ Huang, YJ Zhu, TY Lin, WQ Jiang, HQ Huang, ZM Li - Human pathology, 2011 - Elsevier
Beclin 1 plays a critical role not only in autophagy, but also in apoptosis and differentiation.
The prognostic significance of beclin 1 in diffuse large B-cell lymphoma is largely
unexplored. Immunohistochemical protein expression of beclin 1 in 118 tumor specimens
from patients newly diagnosed with diffuse large B-cell lymphoma treated with rituximab plus
cyclophosphamide, doxorubicin, vincristine, and prednisone regimen from 2003 to 2007
was analyzed. Beclin 1 expression was observed in 101 (85.6%) patients. Low beclin 1 …
The prognostic significance of beclin 1 in diffuse large B-cell lymphoma is largely
unexplored. Immunohistochemical protein expression of beclin 1 in 118 tumor specimens
from patients newly diagnosed with diffuse large B-cell lymphoma treated with rituximab plus
cyclophosphamide, doxorubicin, vincristine, and prednisone regimen from 2003 to 2007
was analyzed. Beclin 1 expression was observed in 101 (85.6%) patients. Low beclin 1 …
