Mechanism of glucose-induced insulin secretion.
CJ Hedeskov - Physiological reviews, 1980 - journals.physiology.org
CJ Hedeskov
Physiological reviews, 1980•journals.physiology.orgIn higher animals the blood glucose concentration is controlled by extremely efficient
homeostatic mechanisms. In humans a high proportion of glucose ingested during a
carbohydrate-rich meal is retained in the liver during a single passage of the portal blood
and comparatively small changes are observed in the glucose concentration of the
peripheral blood. On the other hand, starvation for up to 36-48 h is accompanied by only a
modest decrease in the blood glucose concentration.
homeostatic mechanisms. In humans a high proportion of glucose ingested during a
carbohydrate-rich meal is retained in the liver during a single passage of the portal blood
and comparatively small changes are observed in the glucose concentration of the
peripheral blood. On the other hand, starvation for up to 36-48 h is accompanied by only a
modest decrease in the blood glucose concentration.
In higher animals the blood glucose concentration is controlled by extremely efficient homeostatic mechanisms. In humans a high proportion of glucose ingested during a carbohydrate-rich meal is retained in the liver during a single passage of the portal blood and comparatively small changes are observed in the glucose concentration of the peripheral blood. On the other hand, starvation for up to 36-48 h is accompanied by only a modest decrease in the blood glucose concentration.
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