Differences in vascular pattern between the spontaneous and the transplanted C3H mouse mammary carcinoma
P Falk - European Journal of Cancer and Clinical Oncology, 1982 - Elsevier
The transplanted C3H tumor differs from the spontaneous in its multi-focal origin and in its
increasing loss of differentiation. Loss of differentiation is principally important in that even
the partial branching into lobes, which occurs in the spontaneous tumour, is lost and that the
parenchyma no longer consists of single-layered and multi-layered tubules, as in the
spontaneous tumour, but of multi-layered only. Absence of branching removes the
interlobular pressures, which in spontaneous tumours lead to infarction of the efferent …
increasing loss of differentiation. Loss of differentiation is principally important in that even
the partial branching into lobes, which occurs in the spontaneous tumour, is lost and that the
parenchyma no longer consists of single-layered and multi-layered tubules, as in the
spontaneous tumour, but of multi-layered only. Absence of branching removes the
interlobular pressures, which in spontaneous tumours lead to infarction of the efferent …
