[HTML][HTML] Cell migration: Rho GTPases lead the way
M Raftopoulou, A Hall - Developmental biology, 2004 - Elsevier
M Raftopoulou, A Hall
Developmental biology, 2004•ElsevierRho GTPases control signal transduction pathways that link cell surface receptors to a
variety of intracellular responses. They are best known as regulators of the actin
cytoskeleton, but in addition they control cell polarity, gene expression, microtubule
dynamics and vesicular trafficking. Through these diverse functions, Rho GTPases influence
many aspects of cell behavior. This review will focus specifically on their role in cell
migration.
variety of intracellular responses. They are best known as regulators of the actin
cytoskeleton, but in addition they control cell polarity, gene expression, microtubule
dynamics and vesicular trafficking. Through these diverse functions, Rho GTPases influence
many aspects of cell behavior. This review will focus specifically on their role in cell
migration.
Rho GTPases control signal transduction pathways that link cell surface receptors to a variety of intracellular responses. They are best known as regulators of the actin cytoskeleton, but in addition they control cell polarity, gene expression, microtubule dynamics and vesicular trafficking. Through these diverse functions, Rho GTPases influence many aspects of cell behavior. This review will focus specifically on their role in cell migration.
Elsevier
