Metformin for the treatment of the polycystic ovary syndrome
JE Nestler - New England Journal of Medicine, 2008 - Mass Medical Soc
JE Nestler
New England Journal of Medicine, 2008•Mass Medical SocA 23-year-old woman with the polycystic ovary syndrome presents for evaluation and
possible treatment. She has a family history of diabetes, is obese, and has impaired glucose
tolerance. Metformin therapy is recommended. Metformin increases insulin sensitivity and
may reduce the risk of diabetes. In the polycystic ovary syndrome, long-term metformin
treatment may increase ovulation, improve menstrual cyclicity, and reduce serum androgen
levels.
possible treatment. She has a family history of diabetes, is obese, and has impaired glucose
tolerance. Metformin therapy is recommended. Metformin increases insulin sensitivity and
may reduce the risk of diabetes. In the polycystic ovary syndrome, long-term metformin
treatment may increase ovulation, improve menstrual cyclicity, and reduce serum androgen
levels.
A 23-year-old woman with the polycystic ovary syndrome presents for evaluation and possible treatment. She has a family history of diabetes, is obese, and has impaired glucose tolerance. Metformin therapy is recommended. Metformin increases insulin sensitivity and may reduce the risk of diabetes. In the polycystic ovary syndrome, long-term metformin treatment may increase ovulation, improve menstrual cyclicity, and reduce serum androgen levels.
The New England Journal Of Medicine