[HTML][HTML] Citron kinase is a cell cycle-dependent, nuclear protein required for G2/M transition of hepatocytes
H Liu, F Di Cunto, S Imarisio, LM Reid - Journal of Biological Chemistry, 2003 - ASBMB
Citron Kinase (Citron-K) is a cell cycle-dependent protein regulating the G 2/M transition in
hepatocytes. Synchronization studies demonstrated that expression of the Citron-K protein
starts at the late S and/or the early G 2 phase after that of cyclin B1. Expression of Citron-K is
developmentally regulated. Levels of Citron-K mRNA and protein are highest in embryonic
liver and gradually decrease after birth. Citron-K exists in interphase nuclei and begins to
disperse into the cytoplasm at prophase. It concentrates at the cleavage furrow and midbody …
hepatocytes. Synchronization studies demonstrated that expression of the Citron-K protein
starts at the late S and/or the early G 2 phase after that of cyclin B1. Expression of Citron-K is
developmentally regulated. Levels of Citron-K mRNA and protein are highest in embryonic
liver and gradually decrease after birth. Citron-K exists in interphase nuclei and begins to
disperse into the cytoplasm at prophase. It concentrates at the cleavage furrow and midbody …
