[HTML][HTML] Targeting aneuploidy for cancer therapy
E Manchado, M Malumbres - Cell, 2011 - cell.com
Cell, 2011•cell.com
Tumor cells frequently display an abnormal number of chromosomes, a phenomenon known
as aneuploidy. Tang et al.(2011) now show that aneuploid cells are particularly sensitive to
compounds that induce proteotoxic and energy stress. Could this vulnerability lead to new
cancer therapies?
as aneuploidy. Tang et al.(2011) now show that aneuploid cells are particularly sensitive to
compounds that induce proteotoxic and energy stress. Could this vulnerability lead to new
cancer therapies?
Tumor cells frequently display an abnormal number of chromosomes, a phenomenon known as aneuploidy. Tang et al. (2011) now show that aneuploid cells are particularly sensitive to compounds that induce proteotoxic and energy stress. Could this vulnerability lead to new cancer therapies?
cell.com