Immune response to early and late Histoplasma capsulatum infections
GS Deepe Jr - Current opinion in microbiology, 2000 - Elsevier
Current opinion in microbiology, 2000•Elsevier
Knowledge of the host response to the intracellular pathogenic fungus Histoplasma
capsulatum has increased dramatically. Information has accumulated regarding the cellular
and molecular determinants that lead to resolution of both primary and secondary infection.
The significance of cytokines and other endogenous soluble mediators to the protective
immune response have been analyzed. Moreover, work concerning the relative importance
of T cell subsets to protective immunity has been initiated.
capsulatum has increased dramatically. Information has accumulated regarding the cellular
and molecular determinants that lead to resolution of both primary and secondary infection.
The significance of cytokines and other endogenous soluble mediators to the protective
immune response have been analyzed. Moreover, work concerning the relative importance
of T cell subsets to protective immunity has been initiated.
Knowledge of the host response to the intracellular pathogenic fungus Histoplasma capsulatum has increased dramatically. Information has accumulated regarding the cellular and molecular determinants that lead to resolution of both primary and secondary infection. The significance of cytokines and other endogenous soluble mediators to the protective immune response have been analyzed. Moreover, work concerning the relative importance of T cell subsets to protective immunity has been initiated.
Elsevier