Worldwide racial and ethnic distribution of α1-antitrypsin deficiency: summary of an analysis of published genetic epidemiologic surveys
FJ de Serres - Chest, 2002 - Elsevier
Study objectives α 1-antitrypsin (AAT) deficiency is a genetic disease that is widely known in
Europe as a disease of white individuals, who, along with their descendants in other parts of
the world, are at the highest risk for liver and/or lung disease. There is a limited database of
individuals affected by this disease worldwide. It has been estimated, for example, that there
are 70,000 to 100, 00 individuals affected in the United States, with comparable numbers in
Europe. Study design Genetic epidemiologic studies in the peer-reviewed literature have …
Europe as a disease of white individuals, who, along with their descendants in other parts of
the world, are at the highest risk for liver and/or lung disease. There is a limited database of
individuals affected by this disease worldwide. It has been estimated, for example, that there
are 70,000 to 100, 00 individuals affected in the United States, with comparable numbers in
Europe. Study design Genetic epidemiologic studies in the peer-reviewed literature have …
