Diffuse large B-cell lymphoma: a heterogeneous group of non-Hodgkin lymphomas comprising several distinct clinicopathological entities
P De Paepe, D Wolf-Peeters - Leukemia, 2007 - nature.com
P De Paepe, D Wolf-Peeters
Leukemia, 2007•nature.comDiffuse large B-cell lymphoma (DLBCL) as defined by the World Health Organization (WHO)
classification is clinically, morphologically and genetically a heterogeneous group of
malignant proliferations of large lymphoid B cells. Over the last 6 years, several studies have
been published improving our understanding of these lymphomas. These studies analyzed
DLBCL by their gene expression profile, provided further information on some of the variants
of DLBCL listed in the WHO classification and stressed the impact of the site of origin of …
classification is clinically, morphologically and genetically a heterogeneous group of
malignant proliferations of large lymphoid B cells. Over the last 6 years, several studies have
been published improving our understanding of these lymphomas. These studies analyzed
DLBCL by their gene expression profile, provided further information on some of the variants
of DLBCL listed in the WHO classification and stressed the impact of the site of origin of …
Abstract
Diffuse large B-cell lymphoma (DLBCL) as defined by the World Health Organization (WHO) classification is clinically, morphologically and genetically a heterogeneous group of malignant proliferations of large lymphoid B cells. Over the last 6 years, several studies have been published improving our understanding of these lymphomas. These studies analyzed DLBCL by their gene expression profile, provided further information on some of the variants of DLBCL listed in the WHO classification and stressed the impact of the site of origin of these tumors. This review summarizes these recent data and explores their impact on the recognition of new clinicopathological lymphoma entities.
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