[HTML][HTML] Unmetabolized folic acid in plasma is associated with reduced natural killer cell cytotoxicity among postmenopausal women

AM Troen, B Mitchell, B Sorensen, MH Wener… - The Journal of …, 2006 - Elsevier
Folic acid (FA) supplements and food fortification are used to prevent neural tube defects
and to lower plasma homocysteine. Through exposure to food fortification and vitamin
supplement use, large populations in the United States and elsewhere have an
unprecedented high FA intake. We evaluated dietary and supplemental intakes of folate and
FA in relation to an index of immune function, natural killer cell (NK) cytotoxicity, among 105
healthy, postmenopausal women. Among women with a diet low in folate (< 233 μg/d), those …