[PDF][PDF] Maintaining hematopoietic stem cells in the vascular niche
MJ Kiel, SJ Morrison - Immunity, 2006 - cell.com
MJ Kiel, SJ Morrison
Immunity, 2006•cell.comMaintaining Hematopoietic Stem Cells in the Vascular Niche Page 1 Gothert, JR, Gustin, SE,
Hall, MA, Green, AR, Gottgens, B., Izon, DJ, and Begley, CG (2005). Blood 105, 2724–2732.
Mikkola, HK, and Orkin, SH (2006). Development 133, 3733–3744. Murayama, E., Kissa, K.,
Zapata, A., Mordelet, E., Briolat, V., Lin, H., Handin, R., and Herbomel, P. (2006). Immunity 25,
this issue, 963– 975. Ottersbach, K., and Dzierzak, E. (2005). Dev. Cell 3, 377– 387. Sasaki, K.,
and Sonoda, Y. (2000). Arch. Histol. Cytol. 63, 137– 146. Turpen, JB, Kelley, CM, Mead, PE …
Hall, MA, Green, AR, Gottgens, B., Izon, DJ, and Begley, CG (2005). Blood 105, 2724–2732.
Mikkola, HK, and Orkin, SH (2006). Development 133, 3733–3744. Murayama, E., Kissa, K.,
Zapata, A., Mordelet, E., Briolat, V., Lin, H., Handin, R., and Herbomel, P. (2006). Immunity 25,
this issue, 963– 975. Ottersbach, K., and Dzierzak, E. (2005). Dev. Cell 3, 377– 387. Sasaki, K.,
and Sonoda, Y. (2000). Arch. Histol. Cytol. 63, 137– 146. Turpen, JB, Kelley, CM, Mead, PE …
In this issue of Immunity, Sugiyama et al. (2006) provide evidence that most bone-marrow hematopoietic stem cells (HSCs) reside in vascular niches containing reticular cells that secrete CXCL12, a chemokine that promotes HSC maintenance.
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