Sleep deprivation and energy metabolism: to sleep, perchance to eat?
PD Penev - Current Opinion in Endocrinology, Diabetes and …, 2007 - journals.lww.com
PD Penev
Current Opinion in Endocrinology, Diabetes and Obesity, 2007•journals.lww.comEvolution in an environment with limited resources has established bidirectional links
between sleep and energy homeostasis, the molecular mechanisms of which are emerging
rapidly. Epidemiological data suggest that the unique ability of humans to restrict their sleep
voluntarily in an environment that promotes physical inactivity and overeating may have a
negative impact on metabolic health. Randomized intervention trials are needed to confirm
the validity of this hypothesis.
between sleep and energy homeostasis, the molecular mechanisms of which are emerging
rapidly. Epidemiological data suggest that the unique ability of humans to restrict their sleep
voluntarily in an environment that promotes physical inactivity and overeating may have a
negative impact on metabolic health. Randomized intervention trials are needed to confirm
the validity of this hypothesis.
Summary
Evolution in an environment with limited resources has established bidirectional links between sleep and energy homeostasis, the molecular mechanisms of which are emerging rapidly. Epidemiological data suggest that the unique ability of humans to restrict their sleep voluntarily in an environment that promotes physical inactivity and overeating may have a negative impact on metabolic health. Randomized intervention trials are needed to confirm the validity of this hypothesis.
Lippincott Williams & Wilkins