Increased nuclear proteins in muscle satellite cells in aged animals as compared to young growing animals
S Machida, FW Booth - Experimental gerontology, 2004 - Elsevier
Evidence implies that satellite cells could play some limiting role in aged muscle undergoing
repair or maintenance of mass, which is of potential clinical concern as this could contribute
to sarcopenia. Further, insufficient information is available concerning the cellular
mechanisms responsible for the lower rat satellite cell proliferation in old animals. Thus, it
was hypothesized that the following proteins would be increased in nuclei of satellite cells
from old rat skeletal muscle: the cyclin-dependent kinase (CDK) inhibitors p21WAF1/CIP1 …
repair or maintenance of mass, which is of potential clinical concern as this could contribute
to sarcopenia. Further, insufficient information is available concerning the cellular
mechanisms responsible for the lower rat satellite cell proliferation in old animals. Thus, it
was hypothesized that the following proteins would be increased in nuclei of satellite cells
from old rat skeletal muscle: the cyclin-dependent kinase (CDK) inhibitors p21WAF1/CIP1 …
