[HTML][HTML] The role of endothelial cell apoptosis in inflammatory and immune diseases
RK Winn, JM Harlan - Journal of Thrombosis and Haemostasis, 2005 - Elsevier
The integrity of the endothelial lining of the vasculature is essential for vascular homeostasis
and normal organ function. Endothelial injury or dysfunction has been implicated in the
pathogenesis of diverse vascular diseases. Studies in vitro have demonstrated that a wide
variety of stimuli can induce programmed cell death (apoptosis) of endothelial cells, and
have suggested that apoptosis could be an important mechanism of vascular injury,
resulting in vascular leak, inflammation, and coagulation. In this review, we focus on the …
and normal organ function. Endothelial injury or dysfunction has been implicated in the
pathogenesis of diverse vascular diseases. Studies in vitro have demonstrated that a wide
variety of stimuli can induce programmed cell death (apoptosis) of endothelial cells, and
have suggested that apoptosis could be an important mechanism of vascular injury,
resulting in vascular leak, inflammation, and coagulation. In this review, we focus on the …
