Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric diseases
H Schmid, A Henger, CD Cohen, K Frach… - Journal of the …, 2003 - journals.lww.com
For identifying potential diagnostic markers of proteinuric glomerulopathies, glomerular
mRNA levels of molecules relevant for podocyte function (α-actinin-4, glomerular epithelial
protein 1, Wilms tumor antigen 1, synaptopodin, dystroglycan, nephrin, podoplanin, and
podocin) were determined by quantitative real-time RT-PCR from microdissected glomeruli.
Biopsies from 83 patients with acquired proteinuric diseases were analyzed (minimal
change disease [MCD; n= 13], benign nephrosclerosis [n= 16], membranous …
mRNA levels of molecules relevant for podocyte function (α-actinin-4, glomerular epithelial
protein 1, Wilms tumor antigen 1, synaptopodin, dystroglycan, nephrin, podoplanin, and
podocin) were determined by quantitative real-time RT-PCR from microdissected glomeruli.
Biopsies from 83 patients with acquired proteinuric diseases were analyzed (minimal
change disease [MCD; n= 13], benign nephrosclerosis [n= 16], membranous …
