Effects of β-adrenergic blockers on drug-induced tremors
SI Iwata, M Nomoto, T Fukuda - Pharmacology Biochemistry and Behavior, 1993 - Elsevier
We studied the effect of various kinds of β-adrenergic blockers on oxotremorine-, harmaline-
and thyrotropin-releasing hormone (TRH)-induced tremors in mice. To investigate what
property of β-blockers plays the main role in suppressing tremor, we employed five β-
blockers (propranolol, atenolol, butoxamine, pindolol, and arotinolol). All drugs suppressed
oxotremorine-induced tremors but none reduced harmaline-induced tremors. Even though
TRH-induced tremors were decreased significantly only by propanolol and high doses of …
and thyrotropin-releasing hormone (TRH)-induced tremors in mice. To investigate what
property of β-blockers plays the main role in suppressing tremor, we employed five β-
blockers (propranolol, atenolol, butoxamine, pindolol, and arotinolol). All drugs suppressed
oxotremorine-induced tremors but none reduced harmaline-induced tremors. Even though
TRH-induced tremors were decreased significantly only by propanolol and high doses of …