Chronic lymphocytic leukemia: a proliferative or accumulative disorder?
P Dörmer, H Theml, B Lau - Leukemia Research, 1983 - Elsevier
In two untreated patients with progressive CLL, quantitative 14 C autoradiography of lymph
nodes and, subsequently, continuous infusion of [3 H] thymidine over eight and nine days,
respectively, were performed in order to analyse the lymph node cell kinetics.
Simultaneously, the turnover of labelled lymphocytes in the peripheral blood was evaluated.
From another CLL patient a regional lymph node was removed 6 h after an intralymphatic
flash injection of [3 H] thymidine and sectioned for autoradiographic study of the distribution …
nodes and, subsequently, continuous infusion of [3 H] thymidine over eight and nine days,
respectively, were performed in order to analyse the lymph node cell kinetics.
Simultaneously, the turnover of labelled lymphocytes in the peripheral blood was evaluated.
From another CLL patient a regional lymph node was removed 6 h after an intralymphatic
flash injection of [3 H] thymidine and sectioned for autoradiographic study of the distribution …
