[HTML][HTML] Identification of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 as a negative regulator of thioredoxin function and expression
A Nishiyama, M Matsui, S Iwata, K Hirota… - Journal of Biological …, 1999 - ASBMB
Recent works have shown the importance of reduction/oxidation (redox) regulation in
various biological phenomena. Thioredoxin (TRX) is one of the major components of the
thiol reducing system and plays multiple roles in cellular processes such as proliferation,
apoptosis, and gene expression. To investigate the molecular mechanism of TRX action, we
used a yeast two-hybrid system to identify TRX-binding proteins. One of the candidates,
designated as thioredoxin-binding protein-2 (TBP-2), was identical to vitamin D 3 up …
various biological phenomena. Thioredoxin (TRX) is one of the major components of the
thiol reducing system and plays multiple roles in cellular processes such as proliferation,
apoptosis, and gene expression. To investigate the molecular mechanism of TRX action, we
used a yeast two-hybrid system to identify TRX-binding proteins. One of the candidates,
designated as thioredoxin-binding protein-2 (TBP-2), was identical to vitamin D 3 up …
