Expression of prostaglandin EP2 receptor mRNA in the rat spinal cord

T Kawamura, T Yamauchi, M Koyama, T Maruyama… - Life sciences, 1997 - Elsevier
T Kawamura, T Yamauchi, M Koyama, T Maruyama, T Akira, N Nakamura
Life sciences, 1997Elsevier
RT-PCR and an in situ hybridization analyses demonstrated expression of prostaglandin
EP2 receptor mRNA in the subfield of the dorsal horn of the rat spinal cord. The intensive
signals from the cells labeled with digoxigenin-11-dUTP were scattered through this region
and they corresponded to neurons. EP2 receptor-mediated signal transduction is expected
to play roles in modulating some neuronal functions such as transmission of nociceptive
reaction or motor reflex.
RT-PCR and an in situ hybridization analyses demonstrated expression of prostaglandin EP2 receptor mRNA in the subfield of the dorsal horn of the rat spinal cord. The intensive signals from the cells labeled with digoxigenin-11-dUTP were scattered through this region and they corresponded to neurons. EP2 receptor-mediated signal transduction is expected to play roles in modulating some neuronal functions such as transmission of nociceptive reaction or motor reflex.
Elsevier