Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families
Trends in biochemical sciences, 1999•cell.com
Members of the RNA-helicase family are defined by several evolutionary conserved motifs.
They are found in all organisms–from bacteria to humans–and many viruses. The minimum
number of RNA helicases present within a eukaryotic cell can be predicted from the
complete sequence of the Saccharomyces cerevisiae genome. Recent progress in the
functional analysis of various family members has given new insights into, and confirmed the
significance of these proteins for, most cellular RNA metabolic processes.
They are found in all organisms–from bacteria to humans–and many viruses. The minimum
number of RNA helicases present within a eukaryotic cell can be predicted from the
complete sequence of the Saccharomyces cerevisiae genome. Recent progress in the
functional analysis of various family members has given new insights into, and confirmed the
significance of these proteins for, most cellular RNA metabolic processes.
Abstract
Members of the RNA-helicase family are defined by several evolutionary conserved motifs. They are found in all organisms – from bacteria to humans – and many viruses. The minimum number of RNA helicases present within a eukaryotic cell can be predicted from the complete sequence of the Saccharomyces cerevisiae genome. Recent progress in the functional analysis of various family members has given new insights into, and confirmed the significance of these proteins for, most cellular RNA metabolic processes.
cell.com
