Heart induction: embryology to cardiomyocyte regeneration
A Foley, M Mercola - Trends in cardiovascular medicine, 2004 - Elsevier
Developmental biologists have uncovered many of the signaling proteins that are required
to recruit early embryonic cells to the myocardial lineage. A detailed understanding of their
function should provide insights into the difficult task of inducing embryonic stem cells to
develop cardiomyocyte precursors for cell-based therapies. These proteins may also prove
to be useful to stimulate progenitor cells to differentiate into cardiomyocytes within the
damaged heart.
to recruit early embryonic cells to the myocardial lineage. A detailed understanding of their
function should provide insights into the difficult task of inducing embryonic stem cells to
develop cardiomyocyte precursors for cell-based therapies. These proteins may also prove
to be useful to stimulate progenitor cells to differentiate into cardiomyocytes within the
damaged heart.