[HTML][HTML] The Release of Fibroblast Growth Factor-1 from NIH 3T3 Cells in Response to Temperature Involves the Function of Cysteine Residues (∗)
A Jackson, F Tarantini, S Gamble, S Friedman… - Journal of Biological …, 1995 - ASBMB
Fibroblast growth factor (FGF)-1 is released from NIH 3T3 cells in response to heat shock as
a biologically inactive protein that is unable to bind heparin and requires activation by (NH
4) 2 SO 4 to generate a biologically active extracellular heparin-binding growth factor
(Jackson, A., Friedman, S., Zhan, X., Engleka, KA, Forough, R., and Maciag, T.(1992) Proc.
Natl. Acad. Sci. USA 89, 10691-10695). To further study the mechanism of FGF-1 release in
response to heat shock (42° C), we examined the kinetics of FGF-1 release from FGF-1 …
a biologically inactive protein that is unable to bind heparin and requires activation by (NH
4) 2 SO 4 to generate a biologically active extracellular heparin-binding growth factor
(Jackson, A., Friedman, S., Zhan, X., Engleka, KA, Forough, R., and Maciag, T.(1992) Proc.
Natl. Acad. Sci. USA 89, 10691-10695). To further study the mechanism of FGF-1 release in
response to heat shock (42° C), we examined the kinetics of FGF-1 release from FGF-1 …
