[HTML][HTML] Therapy with a purified plasminogen concentrate in an infant with ligneous conjunctivitis and homozygous plasminogen deficiency

D Schott, CE Dempfle, P Beck… - … England Journal of …, 1998 - Mass Medical Soc
D Schott, CE Dempfle, P Beck, A Liermann, A Mohr-Pennert, M Goldner, P Mehlem…
New England Journal of Medicine, 1998Mass Medical Soc
Ligneous conjunctivitis is a rare disease characterized by acute or chronic recurrent
conjunctivitis in which the conjunctival membranes acquire a wood-like consistency, due
primarily to deposits of fibrin. 1, 2 Corneal involvement and chronic obstruction of the eye
may lead to blindness. The disease is frequently associated with nasopharyngitis,
tracheobronchial obstruction, otitis media, vulvovaginitis, and defective wound healing. 2–9
Pseudomembranous conjunctivitis was first described in 1847 by Bouisson, 10 and the term …
Ligneous conjunctivitis is a rare disease characterized by acute or chronic recurrent conjunctivitis in which the conjunctival membranes acquire a wood-like consistency, due primarily to deposits of fibrin.1,2 Corneal involvement and chronic obstruction of the eye may lead to blindness. The disease is frequently associated with nasopharyngitis, tracheobronchial obstruction, otitis media, vulvovaginitis, and defective wound healing.29 Pseudomembranous conjunctivitis was first described in 1847 by Bouisson,10 and the term “conjunctivitis lignosa” was introduced by Borel in 1933.11 More than 100 cases have been reported in the literature, but no satisfactory treatment has yet been found. The results of therapy . . .
The New England Journal Of Medicine