Association of Polymorphic Trinucleotide Repeat (GAA) n of the Frataxin Gene with Diabetes Mellitus Type 2 in the Moscow Population.

MI Shadrina, OV Miloserdova… - Molecular …, 2002 - search.ebscohost.com
MI Shadrina, OV Miloserdova, PA Slominskii, MI Balabolkin, SA Limborskaya
Molecular Biology, 2002search.ebscohost.com
The article discusses about the association of polymorphic trinucleotide repeat (GAA) n of
the frataxin gene with diabetes mellitus Type 2 in the Moscow population. Diabetes mellitus
type 2 (DM-2) is a heterogeneous disorder that is characterized by disturbed carbohydrate
metabolism, hyperglycemia, and glucosuria, and results from elevated insulin resistance of
tissues and glucose accumulation in the blood. Diabetes mellitus develops in 10% and
glucose tolerance is altered in 30% patients with Friedreich's ataxia.
Abstract
The article discusses about the association of polymorphic trinucleotide repeat (GAA) n of the frataxin gene with diabetes mellitus Type 2 in the Moscow population. Diabetes mellitus type 2 (DM-2) is a heterogeneous disorder that is characterized by disturbed carbohydrate metabolism, hyperglycemia, and glucosuria, and results from elevated insulin resistance of tissues and glucose accumulation in the blood. Diabetes mellitus develops in 10% and glucose tolerance is altered in 30% patients with Friedreich's ataxia.
search.ebscohost.com