Structural and signalling molecules come together at tight junctions

S Tsukita, M Furuse, M Itoh - Current opinion in cell biology, 1999 - Elsevier
S Tsukita, M Furuse, M Itoh
Current opinion in cell biology, 1999Elsevier
Tight junctions (TJs) have been suggested to act both as barriers and fences, but lack of
information on the constituents of TJ strands has hampered the direct assessment of these
functions. Over the past year, our understanding of the molecular architecture of TJ strands
has increased markedly and we are ready to experimentally examine how TJs are involved
in their dual functions.
Tight junctions (TJs) have been suggested to act both as barriers and fences, but lack of information on the constituents of TJ strands has hampered the direct assessment of these functions. Over the past year, our understanding of the molecular architecture of TJ strands has increased markedly and we are ready to experimentally examine how TJs are involved in their dual functions.
Elsevier